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Yonghong Liang Ph.D. Resume

Yonghong Liang Ph.D. Resume

Awọn aseyori nla

Iwadi Iwadi

  • Oṣu Kẹsan. 2006-bayi Ṣiṣẹ si Ph.D (Kemistri Organic)
    ise agbese
    1. Iwadi ti imọ-ọrọ ti ibaraenisọrọ laarin dapivirine (TMC120) ati HIV-1 ẹnjinia transcriptase
    2. Iwadii ìbáṣepọ iṣẹ-ṣiṣe ti o pọju-iṣẹ-ṣiṣe ti awọn diarylpyrimidines ti a ti rọpo benzyl
    3. Awọn imọ-ẹrọ, iyasọtọ ati SAR ti awọn diarylpyrimidines ti a β tabi β naphthyl ti a rọpo gẹgẹ bi awọn alakọja ti kii-nucleoside ti HIV-1 reverse transcriptase
    4. Ṣiṣẹ ati iyasọtọ ti awọn DABO bi awọn alakikan meji ti HIV-1 iyipada transcriptase ati ki o ṣepọ

  • 2003-2006 Titunto si Oludari
    ise agbese
    1. Ilẹ ti ilẹ-ati igbadun-itumọ ti iṣan-proton ti o wa fun 2-hydroxybenzophenone, 8-hydroxy-4H-naphthalen-1-one, 5-hydroxy-4, 5-naphthoquinone, 1-hydroxy-9, 10-anthraquione, 7-Hydroxy -1-indenone, 5, 8-dihydroxy-1, 4-naphthoquinone), 4, 9-dihydroxyperylene-3, 10-quinone ati hypocrellin A ti a ṣe ayẹwo nipasẹ awọn ọna itọtẹlẹ.
    2. Ilẹ-ilẹ-inirmolecular proton gbigbe ni awọn ile-iṣẹ ti 5-hydroxyisoxazole-omi, DNA (RNA) mimọ dimer ati mimọ-N-methylformamide ti a ṣe nipasẹ awọn ọna DFT.
    2002-2003 Atọpọ-ini-ini-ini-ini lori ohun-elo physicochemical ti ketone ati aldehyde

Awards

HUNE OWUN TI AGBAYE AWỌN ỌBA AWỌN ỌBA, 2008

Publications

1. Liang, YH; Chen, FE ONOMOM DFT / PM3 ṣe apejuwe awọn ibaraẹnisọrọ laarinndapivirine ati HIV-1 iyipada transcriptase, iwadi imọ-ọrọ. Awari Discov. Ther. 2007, 1, 57-60.

2. Liang, YH; Chen, FE QSAR iwadi fun awọn diarylpyrimidines lodi si HIV-1 ẹnjinia transcriptase iru-egan ati awọn iyatọ mutant. Eur. J. Med. Chem. 2009, 44, 625-631

3. Liang, YH; Feng, XQ; Zeng, ZS; Chen, FE; Balzarini, J .; Pannecouque, C .; De Clercq, E. Ẹkọ, Ipagun, ati SAR ti Awọn Aṣoju Nipasẹli-Naphthyl-Tipisi bi Awọn alakọja ti kii-Nucleoside ti HIV-1 Reverse Transcriptase. ChemMedChem 2009, 4, 1537-1545.

4. Feng, XQ; Liang, YH; Zeng, ZS; Chen, FE; Balzarini, J .; Pannecouque, C .; De Clercq, E. Awọn atunṣe Ilana ti DAPY Awọn afọwọṣe pẹlu Awọn iṣẹ-egboogi-HIV-1 aṣayan iṣẹ. ChemMedChem 2009, 4, 219.

5. Zeng, ZS; Liang, YH; Feng, XQ; Chen, FE; Balzarini, J .; Pannecouque, C .; De Clercq, E. Imọye ti o ga julọ ti awọn diarylpyrimidines bi awọn inhibitors ti kii-nucleoside HIV-1 yiyipada transcriptase, ChemMedChem 2010, gba.

6. Liang, YH; Yi, PG ijinlẹ iwadi lori ọna, agbara ati ki o ti iṣan-ara ti iṣan proton ti alkannin. Awọn iwe kika fisiksi ti kemikali, 2007, 438, 173.

7. Liang, YH; Yi, PG; Peng, HL Iwadii iwadi ti idasile, idaniloju ati iṣan-ara-gbigbe ti hydrogen gbigbe ti hypocrellin A. Awọn Onimọ Fisiksi ti kemikali, 2008, 466, 6-10.

8. Liang, YH; Yi, PG. Cao, CZ A iwadi imọ-ọrọ lori gbigbe-gbigbe iranlọwọ ti proton-gbigbe ni 5-hydroxyisoxazole. Iwe akosile ti eto eto iṣesi: Theochem, 2005, 729, 163-167.

9. Yi, PG .; Liang, YH; Cao, CZ Ti iṣan ti iṣan tabi hydrogen-atom gbe ni ilẹ ati awọn igbadun ti 2-hydroxybenzophenone: Ayẹwo imọran. Kemikali Kemikali, 2005, 319, 297.

10. Yi, PG .; Liang, YH Awọn imọ-imọ-ọrọ ti iṣọkan ati awọn ipa ti o ni ipa lori gbigbe-iṣan proton ti o wa ni ilẹ ati awọn igbadun igbadun. Kemikali Kemikali, 2006, 322, 382.

11. Yi, PG .; Liang, YH Tang, ZQ Iwadi imọ-ọrọ ti iṣeduro intermolecular proton gbigbe ni awọn ohun elo 5-hydroxyisoxazole-omi. Kemikali Kemikali, 2006, 2006, 322, 387.

12. Liang, YH; Zeng, ZS; Feng, XQ; Chen, FE; Balzarini, J .; Pannecouque, C .; De Clercq, E. Ipagun ti Parallel ati Igbelewọn Biological ti Awọn Diarylpyrimidines pẹlu Agbara Alatako-HIV-1 aṣayan iṣẹ. Med. Chem. 2010, 18 (13), 4601.

13. Liang, YH; Zeng, ZS; Feng, XQ; Chen, FE; Balzarini, J .; Pannecouque, C .; De Clercq, E. Apẹrẹ ti awọn DABO bi awọn alakikan meji ti HIV-1 iyipada transcriptase ati ki o ṣepọ. J. Med. Chem.

14. Chen, FE, Liang, YH Recent Progress on the Multi-target Anti-AIDS Drugs, Progess in Medical Chemistry (8), Peng, SQ Ed., 2011, 167.

15. Chen, FE, Liang, YH, Zeng, ZS PCT / CN2009 / 075931.

16. Zeng, ZS, Liang, YH, Zhang, JY, Xiong, JC China Patent ,, CN201110070027.4

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